Researchers at Case Western Reserve University are investigating to develop artificial intelligence for oral cancer treatment
Researchers at Case Western Reserve University (CWRU) and collaborators in the US and India claim to be using artificial intelligence (AI) to help doctors individually tailor treatments for patients with oral squamous cell carcinomas. A team led by Anant Madabhushi, PhD, the Donnell Institute Professor of Biomedical Engineering at CWRU and director of the Center for Computational Imaging and Personalized Diagnostics (CCIPD), and James Lewis Jr, MD, professor of pathology, microbiology, and immunology at Vanderbilt University Medical Center, has received a five-year, $3.3 million grant from the National Cancer Institute.
On digitized images of oral squamous cell carcinoma tissue slides, the researchers will use advanced computer vision and machine learning techniques to distinguish between cancer and immune cells and then recognize spatial patterns among those cells.
The researchers said: “This technology allows computerized vision to recognize patterns and quantify features that are beyond the human visual system but are powerful indicators of tumor biology. These algorithms will help oncologists and pathologists to then better determine which cancers are more or less aggressive, they added.”
In turn, this will help doctors decide which early-stage cancer patients can safely receive surgery alone versus those who might benefit from postoperative radiation.